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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: STK11 All Species: 41.21
Human Site: Y340 Identified Species: 64.76
UniProt: Q15831 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q15831 NP_000446.1 433 48636 Y340 R S M T V V P Y L E D L H G A
Chimpanzee Pan troglodytes XP_524028 433 48572 Y340 R S M T V V P Y L E D L H G A
Rhesus Macaque Macaca mulatta XP_001093806 433 48511 Y340 R S M T V V P Y L E D L H G A
Dog Lupus familis XP_542206 439 49298 Y340 R G M T V V P Y L E D L H G C
Cat Felis silvestris
Mouse Mus musculus Q9WTK7 436 49248 Y340 R S M T V V P Y L E D L H G R
Rat Rattus norvegicus NP_001101539 436 49227 Y340 R S M T V V P Y L E D L H G R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519859 324 36639 Y241 E N I G K G E Y T I P E D C G
Chicken Gallus gallus Q0GGW5 440 49774 Y340 R S M T A V P Y L E D L H G Y
Frog Xenopus laevis Q91604 432 49054 Y343 R S L T V V P Y L E D L H G Y
Zebra Danio Brachydanio rerio NP_001017839 440 49807 Y339 R S M T V V P Y L E D L H G Y
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_650302 567 62874 Y464 R N S T V I P Y L E A Y H Y G
Honey Bee Apis mellifera XP_623596 434 50409 T342 T I C R H P K T Q E E V P I P
Nematode Worm Caenorhab. elegans Q9GN62 617 69630 S475 R P L T M L S S M T A L Y D G
Sea Urchin Strong. purpuratus XP_780778 429 48923 H337 D L V G E P V H L P L L P D S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q38997 535 61163 I353 G T V T Y Y L I L D N R F R A
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 99.3 92.4 N.A. 90.1 90.5 N.A. 57.7 89.3 81.2 82.2 N.A. 41.4 54.6 29.8 57.7
Protein Similarity: 100 99.3 99.5 94.5 N.A. 93.3 93.1 N.A. 63.2 93.1 87.5 87.2 N.A. 54.8 71.8 43.7 72.2
P-Site Identity: 100 100 100 86.6 N.A. 93.3 93.3 N.A. 6.6 86.6 86.6 93.3 N.A. 53.3 6.6 20 13.3
P-Site Similarity: 100 100 100 86.6 N.A. 93.3 93.3 N.A. 20 86.6 93.3 93.3 N.A. 66.6 20 53.3 33.3
Percent
Protein Identity: N.A. N.A. N.A. 27.4 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 43.7 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 20 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 46.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 7 0 0 0 0 0 14 0 0 0 27 % A
% Cys: 0 0 7 0 0 0 0 0 0 0 0 0 0 7 7 % C
% Asp: 7 0 0 0 0 0 0 0 0 7 60 0 7 14 0 % D
% Glu: 7 0 0 0 7 0 7 0 0 74 7 7 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 7 0 0 % F
% Gly: 7 7 0 14 0 7 0 0 0 0 0 0 0 60 20 % G
% His: 0 0 0 0 7 0 0 7 0 0 0 0 67 0 0 % H
% Ile: 0 7 7 0 0 7 0 7 0 7 0 0 0 7 0 % I
% Lys: 0 0 0 0 7 0 7 0 0 0 0 0 0 0 0 % K
% Leu: 0 7 14 0 0 7 7 0 80 0 7 74 0 0 0 % L
% Met: 0 0 54 0 7 0 0 0 7 0 0 0 0 0 0 % M
% Asn: 0 14 0 0 0 0 0 0 0 0 7 0 0 0 0 % N
% Pro: 0 7 0 0 0 14 67 0 0 7 7 0 14 0 7 % P
% Gln: 0 0 0 0 0 0 0 0 7 0 0 0 0 0 0 % Q
% Arg: 74 0 0 7 0 0 0 0 0 0 0 7 0 7 14 % R
% Ser: 0 54 7 0 0 0 7 7 0 0 0 0 0 0 7 % S
% Thr: 7 7 0 80 0 0 0 7 7 7 0 0 0 0 0 % T
% Val: 0 0 14 0 60 60 7 0 0 0 0 7 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 7 7 0 74 0 0 0 7 7 7 20 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _